Why is it that some tumors progress quickly, while others stop growing on their own or even shrink? Breakthrough research from the laboratory of Technion Distinguished Professor Aaron Ciechanover discovered two proteins that could suppress malignant tumor growth, providing hope for cancer patients everywhere.
As one of the few science and technology institutes in the world with an affiliated medical school and five affiliated hospitals, the Technion is uniquely equipped to combat cancer. Located next to the Rambam Health Care Campus, the Technion Integrated Cancer Center (TICC), led by Professor Ciechanover, takes advantage of its multidisciplinary teams to build on earlier cancer research at the David and Janet Polak Center for Cancer Research and Vascular Biology. Leading scientists, such as Professors Hossam Haick, Marcelle Machluf and Ester Segal, are using nanotechnology to develop targeted drug delivery and personalized medicine. And Technion alumni have put their entrepreneurial know-how to use, bringing new cancer-combating technologies to the marketplace.
The TICC is being led by the generous support of noted philanthropists the Crown Family and Laura and Isaac Perlmutter. To learn more about the TICC, visit http://ticc.technion.ac.il/.
Technion Breakthroughs in Cancer Research
Dopamine Shrinks Cancer Tumors in Mice: By activating the brain’s reward system, Associate Professor Asya Rolls has shrunk cancerous tumors in mice. Triggering the dopaminergic system regulated anti-cancer immunity, suggesting that patients’ positive emotions can control disease progression.
A Treatment that’s Golden: Technion scientists have developed a unique drug delivery technology for cancer treatment that combines infrared light with gold nanoparticles to selectively attack cancer cells without harming healthy tissue in the process.
Nano-Ghost Busters: Working at the cutting edge of cancer research, Professor Marcelle Machluf is reconstructing stem cells to create vesicles that can be used as a targeted drug-delivery vehicle known as “Nano-Ghosts.” The stem cells are emptied of their content (rendering them ghosts) and refilled with treatment (genetic or drugs) that is released upon reaching the targeted tumor. Nano-Ghosts can also carry contrast agents to be used for diagnostics.
Tiny Barcodes Provide a Huge Advance in Personalized Cancer Therapy: Associate Professor Avi Schroeder is personalizing cancer therapy that allows for the testing of several different anticancer drugs inside a patient’s body, concurrently, to determine which will work best.
Click below to watch more Technion videos on the fight against cancer:
Technion Professor Hossam Haick developed the “Electronic Nose” to sniff out diseases, including cancer.
Professor Marcelle Machluf is fighting cancer at the cutting edge of nanotechnology and engineering with her Nano-Ghosts.
Professor Avi Schroeder’s personalized cancer therapy tests the efficacy of different chemotherapies inside a patient’s body prior to treatment.