There are thousands of kinds of bacteria – microscopic, single-celled organisms that are among the earliest known life forms on earth and live in every possible environment all over the world. They might be airborne or found in water, plants, soil, animals and even humans, where some cause dangerous diseases such as salmonella, pneumonia, meningitis, tuberculosis, anthrax, tetanus and botulism.
However, many bacteria, including the ones that comprise the human gut microbiome, do good rather than harm. Bacteria can even be turned into tiny factories that manufacture needed products.
Now, researchers at the Faculty of Biotechnology and Food Engineering at the Technion-Israel Institute of Technology in Haifa have developed “bionic bacteria” that have many potential applications in industry.
Among those applications are the targeted release of biological drugs in the body using external light and other precise medical uses, sensing hazardous substances in the environment and the production of better fuels and other compounds.
The study was led by Assistant Prof. Omer Yehezkeli and doctoral student Oren Bachar, and co-authored by doctoral student Matan Meirovich and master’s student Yara Zeibaq. Their work has just appeared in the international edition of Angewandte Chemie under the title “Protein-Mediated Biosynthesis of Semiconductor Nanocrystals for Photocatalytic NADPH Regeneration and Chiral Amine Production.” The journal, which is published by the German Chemical Society, officially described it as a “hot paper.”
“My research group deals with the interface between engineering and biotechnology at the nanoscale level,” said Yehezkeli. “Our goal is to blur the current boundaries between the different disciplines, and mostly between nanometer materials and biological systems such as bacteria. In our research, we use the unique properties of nanoscale particles on the one hand, and the tremendous selectivity of biological systems on the other, to create bionic systems that perform synergistically.”
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