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Researchers at the Technion — Israel Institute of Technology have developed a first-of-its-kind 3D engineered tissue implant that combines muscle and fat tissue with both blood vessels and a lymphatic network, a step they say could eventually help treat patients with major tissue loss from injuries, burns or cancer surgery.
The findings were published in the journal Cell Biomaterials by an international team led by the Levenberg Laboratory in the Faculty of Biomedical Engineering at the Technion-Israel Institute of Technology.
The current standard treatment for significant tissue loss is an autologous flap, in which tissue is taken from one part of a patient’s body and transplanted to the injured area. Doctors use that method because tissue taken from another person can trigger immune rejection and other complications.
Prof. Shulamit Levenberg, who heads the Technion research group, said the new development could offer a different path.